Nitroquinolines

Cover of: Nitroquinolines |

Published by Raven Press in New York .

Written in English

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Subjects:

  • Nitroquinoline oxide -- Metabolism.,
  • Carcinogenesis.,
  • Nitroquinoline oxide -- Physiological effect.,
  • Nitroquinoline oxide -- Toxicology.

Edition Notes

Includes bibliographies and index.

Book details

Statementeditor, Takashi Sugimura.
SeriesCarcinogenesis--a comprehensive survey ;, v. 6
ContributionsSugimura, Takashi.
Classifications
LC ClassificationsRC268.5 .C36 vol. 6, RC268.7.N57 .C36 vol. 6
The Physical Object
Paginationviii, 159 p. :
Number of Pages159
ID Numbers
Open LibraryOL4904567M
ISBN 100890041628
LC Control Number76051087

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Additional Physical Format: Online version: Nitroquinolines. New York: Raven Press, © (OCoLC) Online version: Nitroquinolines.

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But it also had that charm to it that got to me before long, it definitely picks up /5(). 4-Nitroquinoline 1-oxide (also known as 4-NQO, 4NQO, 4Nqo, NQO and NQNO) is a quinoline derivative and a tumorigenic compound used in the assessment of the efficacy of diets, drugs, and procedures in the prevention and treatment of cancer in animal induces DNA lesions usually corrected by nucleotide excision repair.

General. 4-nitroquinoline 1-oxide Chemical formula: C₉H₆N₂O₃. Go Nitro gets a check for both. While the story is a bit predictable and somewhat underdeveloped, I enjoyed it, and anytime I had to put it down, I couldn't wait to pick it up again to finish it. It was fun, and that's the most important part/5(23).

Environmental mutagens and carcinogens: proceedings of the 3rd International Conference on Environmental Mutagens, Tokyo, Mishima, and Kyoto, Septemberby Takashi Sugimura (Book) 18 editions published in in English.

Nitrosoproline is a nitroso derivative of the amino acid proline. The mixture of nitrosoproline with sodium methoxide is known as PROLI/NO (also PROLINO or ProliNO).

It is an "ultrafast" nitric oxide donor which is being studied for its research and clinical Number: Author interviews, book reviews, editors' picks, and more.

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nitro +‎ quinoline. Noun []. nitroquinoline (plural nitroquinolines) (organic chemistry) Any of several isomeric nitro derivatives of quinoline. This article contains content that is written like an advertisement.

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(October ) (Learn how and when to remove this template message)License: Trialware. Nitroxoline is an antibiotic that has been in use in Europe for about fifty years, and has proven to be very effective at combating biofilm infections.

Nitroxoline was shown to cause a decrease in the biofilm density of P. aeruginosa infections, which would allow access to the infection by the immune system in vivo.

It was shown that nitroxoline functions by chelating Fe 2+ and Zn 2+ ATC code: J01XX07 (WHO). Nucleophilic substitution of hydrogen in electron-deficient arenes, particularly nitroarenes, is an efficient and versatile tool for introduction of a variety of C, N, O, and other substituents.

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A divergent synthesis of functionalized quinolines was achieved from anilines and two distinct amino acids, and (17JOC). Human leishmaniasis is a major public health problem with a wide clinical spectrum.

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Electrophilic substitution reactions: Electron localization energies calculated by Acheson and Goodall suggest that quinolizinium salts are unreactive toward electrophilic attack.

However, bromination is an exception; bromine first reacts with quinolizinium bromide in a reversible process to form perbromide, which under drastic S E Ar conditions leads to the generation of 1.

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Nitroquinolines readily react with alkanethiols in tetrahydrofuran in the presence of excess sodium hydride to give the corresponding alkylthio derivatives via the preferential displacement of a ring hydrogen atom adjacent to the nitro an induction period, the reaction starts and completes within a short time even at low temperature, suggesting the involvement of a radical .Add, delete, and modify text and images in PDF files with intuitive editing tools.

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